{"id":3934,"date":"2018-08-13T03:03:20","date_gmt":"2018-08-13T03:03:20","guid":{"rendered":"https:\/\/glutenfreepleasure.com\/__proxy_domain\/slclinic.com.sg\/?p=3934"},"modified":"2025-08-21T16:13:14","modified_gmt":"2025-08-21T08:13:14","slug":"melasma-treatment-singapore","status":"publish","type":"post","link":"https:\/\/glutenfreepleasure.com\/__proxy_domain\/slclinic.com.sg\/melasma-treatment-singapore\/","title":{"rendered":"Your Oral Medication for Melasma"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3934\" class=\"elementor elementor-3934\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t<div data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-element elementor-element-441e58cb e-flex e-con-boxed e-con e-parent\" data-id=\"441e58cb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2c9304a0 elementor-widget elementor-widget-text-editor\" data-id=\"2c9304a0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Do you suffer from patchy pigmentation on your cheeks or forehead? Have you tried many whitening products, lasers and even chemical peels without significant improvement? If you do, you may benefit from a <a href=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/slclinic.com.sg\/skin\/pigmentation-laser-singapore\/\">skin pigmentation treatment in Singapore<\/a> which has been shown to help with your pigmentation problem.<\/p>\n<h2>What is Melasma?<\/h2>\n<p>Melasma is a common skin condition that causes brown or greyish-brown patches, usually on areas exposed to the sun &#8211; most often the cheeks, forehead, nose, upper lip, and chin.<\/p>\n<p data-start=\"562\" data-end=\"867\">Melasma is more common in women, especially those with medium to darker skin tones, and often develops during periods of hormonal changes, such as pregnancy, oral contraceptive use, or hormone therapy.&nbsp;<\/p>\n<h2>Common Causes and Triggers of Melasma<\/h2>\n<p><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/slclinic.com.sg\/wp-content\/uploads\/2025\/06\/Pathophysiology-of-Melasma-1.jpg\" alt=\"\" width=\"1973\" height=\"1405\"><\/p>\n<p>Melasma occurs when melanocytes, the pigment-producing cells in the skin, become overactive and produce too much melanin (the pigment that gives skin its colour).<\/p>\n<p data-start=\"217\" data-end=\"500\">When your skin is exposed to sunlight, heat, or hormonal changes, your skin cells (called <strong data-start=\"307\" data-end=\"324\">keratinocytes<\/strong>) send signals that trigger <strong data-start=\"352\" data-end=\"379\">melanin-producing cells<\/strong> (<strong data-start=\"381\" data-end=\"396\">melanocytes<\/strong>) to make more pigment. Over time, these signals become too active, leading to dark patches on the skin.<\/p>\n<p data-start=\"502\" data-end=\"529\">Other changes happen too:<\/p>\n<ul data-start=\"530\" data-end=\"946\">\n<li data-start=\"530\" data-end=\"608\">\n<p data-start=\"532\" data-end=\"608\"><strong data-start=\"532\" data-end=\"554\">More blood vessels<\/strong> form in the area, which can fuel more pigmentation.<\/p>\n<\/li>\n<li data-start=\"609\" data-end=\"715\">\n<p data-start=\"611\" data-end=\"715\"><strong data-start=\"611\" data-end=\"625\">Mast cells<\/strong>, part of your immune system, release substances that increase inflammation and pigment.<\/p>\n<\/li>\n<li data-start=\"716\" data-end=\"808\">\n<p data-start=\"718\" data-end=\"808\"><strong data-start=\"718\" data-end=\"732\">Oil glands<\/strong> (sebaceous glands) may also play a role by reacting to hormones and heat.<\/p>\n<\/li>\n<li data-start=\"809\" data-end=\"946\">\n<p data-start=\"811\" data-end=\"946\">The <strong data-start=\"815\" data-end=\"842\">skin\u2019s foundation layer<\/strong> (basement membrane) can become damaged, letting pigment sink deeper and making melasma harder to treat.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"948\" data-end=\"1099\">So even though melasma looks like just dark patches, it\u2019s actually a mix of pigmentation, inflammation, hormonal activity, and structural skin changes. Other factors that trigger melasma include genetics, skincare products and stress.&nbsp;<\/p>\n<h2>How Melasma Manifests: Symptoms and Affected Areas<\/h2>\n<p>Melasma usually presents as symmetrical, brownish patches on sun-exposed areas of the skin. The most affected regions include the:<\/p>\n<ul>\n<li aria-level=\"1\"><strong>Cheeks<\/strong><\/li>\n<li aria-level=\"1\"><strong>Forehead<\/strong><\/li>\n<li aria-level=\"1\"><strong>Nose bridge<\/strong><\/li>\n<li aria-level=\"1\"><strong>Upper lip<\/strong><\/li>\n<\/ul>\n<p>In some cases, melasma can also affect the neck and forearms. The skin pigmentation is not raised or inflamed but can vary in intensity and may darken over time without proper treatment or protection from sun exposure.<\/p>\n<h2>Oral Medication Used for Melasma<\/h2>\n<p>Over-the-counter whitening products used to lighten pigmentation show limited results on Melasma, and topical medications and medical laser treatments on their own can sometimes produce marginal improvements. Melasma is also challenging to treat as it tends to recur with time and sun exposure.<\/p>\n<p>Fortunately, researchers at Singapore\u2019s National Skin Centre found that the Oral Medication for Pigmentation, used in treating heavy menstrual periods, showed significant lightening of Melasma in over 90 per cent of patients it studied.<\/p>\n<h2>How Oral Medications Work to Treat Melasma<\/h2>\n<p>Oral Medication for Pigmentation is proposed to reduce pigmentation by inhibiting UV-induced melanocyte (cells that produce melanin) activation. Oral Medication for Pigmentation can also stabilise the blood vessels and reduce skin inflammation, a contributing factor in melasma.<\/p>\n<p>Side effects are minimal with the medication, it is generally suitable for those in good health. Contraindications include those with a personal\/family history of blood disorders, pregnant women, and ladies on oral contraceptive pills.<\/p>\n<h2>Comparing Oral Treatments to Topical Solutions<\/h2>\n<p>When deciding between Oral Medication for Pigmentation and topical treatments for pigmentation, it\u2019s important to consider the pros and cons of each.<\/p>\n<ul>\n<li aria-level=\"1\"><b>Topical treatments<\/b> such as Depigmentation Cream, Acne Cream, and corticosteroids act directly on the skin to inhibit melanin production and promote exfoliation. These solutions are usually applied daily and can take several weeks or months to show results. They are ideal for mild to moderate cases of melasma but may be less effective for deep pigmentation or resistant cases.<\/li>\n<li aria-level=\"1\"><b>Oral medication<\/b> targets pigmentation from within. It offers an alternative for those who have not seen improvement with topical solutions or who suffer from more severe melasma. Oral medication is convenient and can offer faster, more noticeable results, though it requires medical supervision.<\/li>\n<\/ul>\n<h2>What are Other Treatments for Melasma?<\/h2>\n<p>Besides oral and topical medications, several other treatments can be effective in managing melasma, including:<\/p>\n<ul>\n<li aria-level=\"1\"><strong>Chemical peels:<\/strong> Exfoliating the skin to remove pigmented cells.<\/li>\n<li aria-level=\"1\"><strong>Laser treatment:<\/strong> Targeting pigment with light energy to break it down.<\/li>\n<li aria-level=\"1\"><strong>Radiofrequency Microneedling:<\/strong> Repair of the dermal-epidermal junction and reducing inflammation that triggers hyperpigmentation. Stimulating collagen production to improve skin texture and tone.<\/li>\n<li aria-level=\"1\"><strong>Sun protection:<\/strong> The most essential step in preventing melasma is diligent sun protection with broad-spectrum sunscreens.<\/li>\n<\/ul>\n<p>Do you suffer from patchy pigmentation and want to know if you\u2019ll benefit from this treatment? Speak to any of our doctors at <a href=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/slclinic.com.sg\/\">SL Aesthetic Clinic<\/a> and we\u2019ll be happy to advise on the pigmentation removal treatments most suited for you.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0d2b961 elementor-widget elementor-widget-heading\" data-id=\"0d2b961\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">FAQ<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc1a94f elementor-widget elementor-widget-accordion\" data-id=\"dc1a94f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h3 id=\"elementor-tab-title-2301\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-2301\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Common Oral Medications for Melasma<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t<div id=\"elementor-tab-content-2301\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-2301\"><p>The most commonly prescribed oral medications for melasma include:<\/p><ul><li aria-level=\"1\">Oral Medication for Pigmentation<\/li><li aria-level=\"1\">Polypodium leucotomos extract<\/li><li aria-level=\"1\">Glutathione<\/li><\/ul><p>These medications can be used on their own or in combination with other treatments to improve pigmentation issues.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h3 id=\"elementor-tab-title-2302\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-2302\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">How Long Before You See Results?<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t<div id=\"elementor-tab-content-2302\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-2302\"><p>Results from oral treatments typically take about 4 to 8 weeks to become noticeable. However, it\u2019s essential to continue the treatment for several months to maintain the effects and prevent recurrence.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h3 id=\"elementor-tab-title-2303\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-2303\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Who Should Avoid Oral Treatments For Melasma?<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t<div id=\"elementor-tab-content-2303\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-2303\"><p>Oral medications for melasma may not be suitable for:<\/p><ul><li>Pregnant or breastfeeding women<\/li><li>Individuals with conditions such as blood clotting disorders<\/li><li>People with known allergies to any of the ingredients<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h3 id=\"elementor-tab-title-2304\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-2304\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Potential Side Effects of Oral Medications<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t<div id=\"elementor-tab-content-2304\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-2304\"><p>While generally well-tolerated, oral medications can have side effects, including:<\/p><ul><li>Gastrointestinal issues (nausea, stomach discomfort)<\/li><li>Blood clotting concerns (for Oral Medication for Pigmentation)<\/li><li>Potential allergic reactions<\/li><\/ul><p>Please consult your doctor before starting any oral medication for melasma.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h3 id=\"elementor-tab-title-2305\" class=\"elementor-tab-title\" data-tab=\"5\" role=\"button\" aria-controls=\"elementor-tab-content-2305\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Can Oral and Topical Medications Be Combined To Treat Melasma?<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t<div id=\"elementor-tab-content-2305\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"5\" role=\"region\" aria-labelledby=\"elementor-tab-title-2305\"><p>Yes, combining oral medications with topical treatments often leads to better outcomes for melasma patients. This combination addresses pigmentation both on the surface and internally, providing a more comprehensive approach.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<h3 id=\"elementor-tab-title-2306\" class=\"elementor-tab-title\" data-tab=\"6\" role=\"button\" aria-controls=\"elementor-tab-content-2306\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Can Oral Medications Be Used With Cosmetic Treatments?<\/a>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t<div id=\"elementor-tab-content-2306\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"6\" role=\"region\" aria-labelledby=\"elementor-tab-title-2306\"><p>Oral medications can complement cosmetic anti-pigmentation treatments like chemical peels, microneedling, or laser therapy. These combined approaches often lead to faster and more significant improvements in skin pigmentation, though they should be done under the supervision of a doctor to minimise risks.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<script type=\"application\/ld+json\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Common Oral Medications for Melasma\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>The most commonly prescribed oral medications for melasma include:<\\\/p><ul><li aria-level=\\\"1\\\">Oral Medication for Pigmentation<\\\/li><li aria-level=\\\"1\\\">Polypodium leucotomos extract<\\\/li><li aria-level=\\\"1\\\">Glutathione<\\\/li><\\\/ul><p>These medications can be used on their own or in combination with other treatments to improve pigmentation issues.<\\\/p>\"}},{\"@type\":\"Question\",\"name\":\"How Long Before You See Results?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>Results from oral treatments typically take about 4 to 8 weeks to become noticeable. However, it\\u2019s essential to continue the treatment for several months to maintain the effects and prevent recurrence.<\\\/p>\"}},{\"@type\":\"Question\",\"name\":\"Who Should Avoid Oral Treatments For Melasma?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>Oral medications for melasma may not be suitable for:<\\\/p><ul><li>Pregnant or breastfeeding women<\\\/li><li>Individuals with conditions such as blood clotting disorders<\\\/li><li>People with known allergies to any of the ingredients<\\\/li><\\\/ul>\"}},{\"@type\":\"Question\",\"name\":\"Potential Side Effects of Oral Medications\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>While generally well-tolerated, oral medications can have side effects, including:<\\\/p><ul><li>Gastrointestinal issues (nausea, stomach discomfort)<\\\/li><li>Blood clotting concerns (for Oral Medication for Pigmentation)<\\\/li><li>Potential allergic reactions<\\\/li><\\\/ul><p>Please consult your doctor before starting any oral medication for melasma.<\\\/p>\"}},{\"@type\":\"Question\",\"name\":\"Can Oral and Topical Medications Be Combined To Treat Melasma?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>Yes, combining oral medications with topical treatments often leads to better outcomes for melasma patients. This combination addresses pigmentation both on the surface and internally, providing a more comprehensive approach.<\\\/p>\"}},{\"@type\":\"Question\",\"name\":\"Can Oral Medications Be Used With Cosmetic Treatments?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<p>Oral medications can complement cosmetic anti-pigmentation treatments like chemical peels, microneedling, or laser therapy. These combined approaches often lead to faster and more significant improvements in skin pigmentation, though they should be done under the supervision of a doctor to minimise risks.<\\\/p>\"}}]}<\/script>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Do you suffer from patchy pigmentation on your cheeks or forehead? Have you tried many whitening products, lasers and even chemical peels without significant improvement? If you do, you may benefit from a skin pigmentation treatment in Singapore which has been shown to help with your pigmentation problem. What is Melasma? Melasma is a common [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":10438,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"class_list":["post-3934","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Melasma Treatment In Singapore | SL Aesthetic Clinic<\/title>\n<meta name=\"description\" content=\"Suffering from patchy pigmentation &amp; want to know if you\u2019ll benefit from the oral treatment for melasma? 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