{"id":124,"date":"2025-05-14T10:21:38","date_gmt":"2025-05-14T10:21:38","guid":{"rendered":"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/?page_id=124"},"modified":"2026-10-14T05:02:19","modified_gmt":"2026-10-14T05:02:19","slug":"management-of-primary-hyperaldosteronism","status":"publish","type":"page","link":"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/management-of-primary-hyperaldosteronism\/","title":{"rendered":"Management of Primary Hyperaldosteronism"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Aldosterone excess can cause muscle cramps or weakness due to low potassium levels affecting normal muscle function.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Aldosterone suppression refers to the medical management of conditions where the body produces too much aldosterone. Excess aldosterone is a recognised and treatable cause of secondary hypertension and can significantly increase cardiovascular risk if left unaddressed. It is thought to account for 5 to 10 percent of all hypertension and is reversible.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Because its effects are often silent in the early stages, many people are diagnosed only during evaluation for resistant high blood pressure or unexplained low potassium levels. Targeted testing allows clinicians to identify the cause and initiate appropriate treatment to restore hormonal balance.It is important to treat because the hypertension from primary hyperaldosteronism causes more heart attacks and strokes than normal stock-standard \u2018essential hypertension\u2019.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What is aldosterone?&nbsp;<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Aldosterone is a <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8859437\/\">mineralocorticoid steroid hormone<\/a> produced by the adrenal glands that plays a central role in regulating blood pressure, sodium balance and potassium levels. It signals the kidneys to retain sodium and water while excreting potassium. This process helps maintain blood volume and stable circulation.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When aldosterone is produced in excess, the body <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499983\/\">retains too much sodium and loses too much potassium<\/a>. This can result in persistent or difficult-to-control high blood pressure, low potassium levels and long-term cardiovascular strain. Identifying and treating aldosterone excess early is important to reduce complications and protect heart and kidney health.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What is aldosterone excess?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Aldosterone excess most commonly occurs in a condition known as primary hyperaldosteronism (Conn\u2019s syndrome). In this disorder, one or both adrenal glands produce aldosterone independently of the body\u2019s normal regulatory mechanisms.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Excess aldosterone leads to:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Increased sodium retention<\/li>\n\n\n\n<li>Increased water retention<\/li>\n\n\n\n<li>Suppression of renin<\/li>\n\n\n\n<li>Excess potassium loss<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Over time, this contributes to hypertension that may be resistant to standard blood pressure medications and can increase the risk of heart disease, stroke and kidney damage.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What causes aldosterone excess?&nbsp;<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Aldosterone levels may rise when the adrenal glands produce the hormone in excess (termed Primary Hyperaldosteronism. Understanding the cause is essential for selecting the most effective treatment.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Unilateral adrenal adenoma <\/strong>\u2014<strong> <\/strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539906\/\">a benign (non-cancerous) tumour<\/a> in one adrenal gland that produces aldosterone independently of the body\u2019s normal regulatory system, leading to persistent hormone overproduction.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Bilateral adrenal hyperplasia <\/strong>\u2014 <a href=\"https:\/\/www.cancertherapyadvisor.com\/home\/decision-support-in-medicine\/labmed\/bilateral-hyperplasia-of-the-adrenal-gland\/\">enlargement and increased activity of both adrenal glands<\/a>, causing them to release excess aldosterone without a single identifiable tumour.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Rare genetic conditions<\/strong> \u2014 inherited disorders, such as familial hyperaldosteronism, that alter how the adrenal glands regulate aldosterone production and can lead to early or recurrent hormone excess.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25-1024x1024.jpeg\" alt=\"\" class=\"wp-image-1256\" srcset=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25-1024x1024.jpeg 1024w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25-300x300.jpeg 300w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25-150x150.jpeg 150w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25-768x768.jpeg 768w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25-1536x1536.jpeg 1536w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-25.jpeg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Primary hyperaldosteronism (Conn\u2019s syndrome) is a condition where the adrenal glands produce too much aldosterone, leading to high blood pressure and low potassium levels.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What are the symptoms of aldosterone excess?&nbsp;<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Excess aldosterone affects blood pressure regulation and electrolyte balance. Symptoms often develop gradually and may go unnoticed until evaluation for persistent hypertension or abnormal potassium levels.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>High blood pressure<\/strong> \u2014 persistent or difficult-to-control hypertension caused by increased sodium retention.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Low potassium levels<\/strong> \u2014 fatigue, cramps or muscle weakness due to excessive loss of potassium in the urine.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Muscle cramps or weakness<\/strong> \u2014 resulting from an electrolyte imbalance affecting normal muscle function.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Excessive thirst<\/strong> \u2014 increased fluid needs as the body attempts to correct the altered sodium balance.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Frequent urination<\/strong> \u2014 higher urine output linked to changes in kidney handling of sodium and potassium.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How is aldosterone excess diagnosed?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Diagnosis involves a combination of blood tests, imaging studies and clinical evaluation. These assessments help identify the source of the imbalance and guide appropriate treatment planning.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Aldosterone\u2013renin ratio (ARR) <\/strong>\u2014 a blood test that <a href=\"https:\/\/primaryaldosteronism.org\/step-1-aldosterone-renin-ratio-arr\/\">compares aldosterone and renin levels<\/a>. When aldosterone is elevated while renin is suppressed, the resulting high ratio raises suspicion for primary hyperaldosteronism.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Confirmatory testing <\/strong>\u2014 may include saline suppression testing or other hormone assessments to confirm inappropriate aldosterone production.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Electrolyte testing <\/strong>\u2014 measurement of potassium and sodium levels.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Adrenal imaging (CT scan) <\/strong>\u2014 identifies structural abnormalities such as adenomas. Done after confirmation of hyperaldosteronism.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Adrenal vein sampling (when required) <\/strong>\u2014 <a href=\"https:\/\/primaryaldosteronism.org\/step-4-adrenal-venous-sampling\/\">a specialised procedure<\/a> used to determine whether excess aldosterone originates from one or both adrenal glands before surgery is considered.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Medication review is essential, as certain blood pressure drugs can affect renin and aldosterone levels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What are the treatment options for aldosterone excess?&nbsp;<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Treatment depends on the underlying cause, the severity of symptoms and findings on blood tests or imaging. Most cases respond well to medication, while some require targeted procedures or specialist care.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Aldosterone-blocking medications <\/strong>\u2014 <a href=\"https:\/\/primaryaldosteronism.org\/medical-option\/\">drugs such as spironolactone or eplerenone <\/a>that reduce aldosterone activity and help control blood pressure.&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Blood pressure management <\/strong>\u2014 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10765166\/\">structured antihypertensive therapy<\/a> to stabilise readings affected by aldosterone excess.&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Potassium supplementation <\/strong>\u2014 correcting low potassium levels when required for safety and symptom relief.&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Minimally invasive adrenal surgery <\/strong>\u2014 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11222333\/\">laparoscopic adrenalectomy<\/a> may be recommended for confirmed unilateral aldosterone-producing adenomas. Surgery can significantly improve or even cure hypertension in selected patients.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Long-term monitoring \u2014 <\/strong>regular hormone testing, blood pressure checks and symptom review to ensure ongoing safety and effectiveness.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What to expect during aldosterone suppression<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Treatment for aldosterone involves ongoing supervision to ensure hormone levels return to a safe range and symptoms improve steadily. Regular monitoring helps guide adjustments and prevents complications.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Regular blood pressure checks<\/strong> \u2014 tracking blood pressure to assess response to aldosterone-blocking treatment.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Repeat hormone testing <\/strong>\u2014 measuring aldosterone and renin levels periodically ensures treatment is suppressing excess hormone activity appropriately.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Electrolyte monitoring <\/strong>\u2014 checking potassium and sodium levels helps detect and prevent imbalances caused by the condition or its treatment.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Kidney function tests <\/strong>\u2014 assessing renal function ensures medications remain safe and do not adversely affect kidney health.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Medication dose adjustments <\/strong>\u2014 doses may be modified based on blood pressure response, laboratory results and overall clinical progress.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Potential benefits of curing Primary Hyperaldosteronism<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Effective treatment of aldosterone excess can improve blood pressure control, restore electrolyte balance and reduce long-term cardiovascular risk. Outcomes depend on the underlying cause and how early the condition is identified.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Improved blood pressure control <\/strong>\u2014 blocking aldosterone reduces sodium and water retention, helping stabilise blood pressure, particularly in resistant hypertension.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Reduced reliance on multiple medications<\/strong> \u2014 targeted treatment may lower the number or dosage of antihypertensive drugs required over time.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Correction of potassium levels<\/strong> \u2014 restoring normal potassium improves muscle function, reduces cramps and prevents complications linked to chronic hypokalaemia.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Lower cardiovascular risk <\/strong>\u2014 treating aldosterone excess decreases strain on the heart and blood vessels, reducing the risk of stroke, heart enlargement and heart failure and bringing it back down to levels of the normal person.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Protection of kidney function<\/strong> \u2014 proper hormonal control helps prevent long-term kidney damage associated with uncontrolled hypertension.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Improved overall well-being<\/strong> \u2014 many patients experience better energy levels and physical comfort once blood pressure and electrolyte balance are stabilised.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Risks and precautions for aldosterone suppression&nbsp;<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">While treatment is generally safe, certain considerations apply.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Medication side effects<\/strong> \u2014 <a href=\"https:\/\/www.bad.org.uk\/pils\/spironolactone\">spironolactone may cause<\/a> breast tenderness, menstrual irregularities or elevated potassium. Eplerenone has fewer hormonal side effects but may still affect potassium levels.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Kidney function considerations<\/strong> \u2014 reduced kidney function requires careful monitoring.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Risk of high potassium (hyperkalaemia) <\/strong>\u2014 particularly in patients with kidney disease or those on certain blood pressure medications.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Surgical risks<\/strong> \u2014 as with any procedure, adrenal surgery carries standard operative risks, though laparoscopic approaches are generally safe.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Specialist endocrine assessment ensures appropriate selection and safe management.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Summary<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Aldosterone excess is a treatable hormonal condition that commonly presents as resistant hypertension and may be associated with low potassium levels. Primary hyperaldosteronism is one of the most underdiagnosed causes of secondary hypertension. Early detection through proper hormonal testing allows targeted treatment, which may include medication or minimally invasive surgery. With appropriate management and monitoring, blood pressure control improves and long-term cardiovascular risk can be significantly reduced.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you have persistent high blood pressure, low potassium levels or hypertension that is difficult to control, <a href=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/contact\/\">schedule a consultation<\/a> with The Metabolic Clinic for a comprehensive endocrine evaluation and personalised treatment plan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Frequently Asked Questions (FAQs)&nbsp;<\/strong><\/h2>\n\n\n<div class=\"alignnone\"><style>#sp-ea-1259 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-1259.sp-easy-accordion>.sp-ea-single {margin-bottom: 10px; border: 1px solid #e2e2e2; }#sp-ea-1259.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #feffed;}#sp-ea-1259.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #fff; color: #183122;}#sp-ea-1259.sp-easy-accordion>.sp-ea-single {background: #667861;}#sp-ea-1259.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: left; color: #444;font-size: 16px;}<\/style><div id=\"sp_easy_accordion-1776270912\"><div id=\"sp-ea-1259\" class=\"sp-ea-one sp-easy-accordion\" data-ea-active=\"ea-click\" data-ea-mode=\"vertical\" data-preloader=\"\" data-scroll-active-item=\"\" data-offset-to-scroll=\"0\"><div class=\"ea-card ea-expand sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12590\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12590\" aria-controls=\"collapse12590\" href=\"#\" aria-expanded=\"true\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-minus\"><\/i> Is aldosterone excess common?<\/a><\/h3><div class=\"sp-collapse spcollapse collapsed show\" id=\"collapse12590\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12590\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Primary hyperaldosteronism is more common than previously thought and may account for <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5461126\/\"><span style=\"font-weight: 400\">5\u201310% of hypertension cases<\/span><\/a><span style=\"font-weight: 400\">, particularly resistant hypertension.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12591\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12591\" aria-controls=\"collapse12591\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Does aldosterone excess always cause low potassium?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12591\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12591\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">No. Many patients have normal potassium levels, especially in early stages.Though this is the number one marker that someone may have primary hyperaldosteronism.\u00a0<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12592\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12592\" aria-controls=\"collapse12592\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can aldosterone excess be cured?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12592\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12592\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Unilateral adenomas can often be treated surgically. Bilateral disease is usually managed long term with medication.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12593\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12593\" aria-controls=\"collapse12593\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Will blood pressure return to normal after aldosterone suppression?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12593\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12593\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Blood pressure often improves significantly. Some patients may still require reduced-dose medication expecially if they have had the condition for a long time thus causing permanent stiffening of arteries.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12594\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12594\" aria-controls=\"collapse12594\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Is lifelong treatment required for excess aldosterone?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12594\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12594\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">That depends on the cause. Bilateral adrenal overactivity typically requires long-term medication, while surgery may be definitive for unilateral disease.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12595\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12595\" aria-controls=\"collapse12595\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Does salt intake affect aldosterone levels?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12595\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12595\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">High sodium intake can worsen blood pressure in aldosterone excess, but dietary restriction alone does not treat the underlying hormonal problem.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12596\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12596\" aria-controls=\"collapse12596\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can aldosterone excess increase heart risk?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12596\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12596\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes. Untreated aldosterone excess increases the risk of heart enlargement, stroke and kidney disease.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12597\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12597\" aria-controls=\"collapse12597\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Who should be tested for primary hyperaldosteronism?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12597\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12597\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Testing is recommended for individuals with resistant hypertension, high blood pressure at a young age, unexplained low potassium levels or an adrenal nodule detected on imaging.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12598\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12598\" aria-controls=\"collapse12598\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can primary hyperaldosteronism occur without symptoms?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12598\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12598\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes. Some people have no obvious symptoms and are diagnosed only during evaluation for difficult-to-control hypertension.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12599\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12599\" aria-controls=\"collapse12599\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Is aldosterone excess the same as Cushing\u2019s syndrome?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse12599\" data-parent=\"#sp-ea-1259\" role=\"region\" aria-labelledby=\"ea-header-12599\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">No. Aldosterone excess involves abnormal mineralocorticoid production affecting blood pressure and potassium, while Cushing\u2019s syndrome is caused by excess cortisol and presents with different hormonal features.<\/span><\/p><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Management of primary hyperaldosteronism involves diagnosing the source of excess aldosterone and treating it to lower blood pressure and reduce cardiovascular risk.<\/p>\n","protected":false},"author":1,"featured_media":1255,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"page_category":[10],"class_list":["post-124","page","type-page","status-publish","has-post-thumbnail","hentry","page_category-endocrine-therapy"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Primary Hyperaldosteronism Singapore | Conn\u2019s Syndrome<\/title>\n<meta name=\"description\" content=\"Learn about primary hyperaldosteronism in Singapore, including symptoms, causes, diagnosis, adrenal vein sampling and medical 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