{"id":65,"date":"2025-05-14T08:49:54","date_gmt":"2025-05-14T08:49:54","guid":{"rendered":"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/?page_id=65"},"modified":"2026-09-02T06:27:45","modified_gmt":"2026-09-02T06:27:45","slug":"hypoparathyroidism-underactive-parathyroid","status":"publish","type":"page","link":"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/hypoparathyroidism-underactive-parathyroid\/","title":{"rendered":"Hypoparathyroidism\/ Underactive Parathyroid"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">What is hypoparathyroidism?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hypoparathyroidism, sometimes referred to as underactive parathyroid, is a rare endocrine disorder in which the parathyroid glands fail to produce enough parathyroid hormone (PTH). The parathyroid glands are four small glands located in the neck, adjacent to the thyroid, and they play a vital role in regulating calcium and phosphate balance in the body. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK499940\/\" target=\"_blank\" rel=\"noreferrer noopener\">PTH is essential for maintaining stable levels of calcium<\/a> in the blood by controlling how calcium is absorbed from food in the gut, released from bones, and reabsorbed by the kidneys.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When the body does not produce sufficient PTH, calcium levels in the blood fall (<a href=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/hypocalcemia-low-calcium\/\" type=\"page\" id=\"69\">hypocalcaemia<\/a>), while phosphate levels often rise (hyperphosphataemia). This imbalance can disrupt the normal functioning of muscles, nerves, and many internal organs. Patients may experience tingling or numbness in the lips, hands, and feet, muscle cramps or spasms, fatigue, and in more severe cases, seizures or cardiac complications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Hypoparathyroidism may develop for several reasons. The most common cause is accidental <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9350047\/\" target=\"_blank\" rel=\"noreferrer noopener\">damage or removal of the parathyroid glands during surgery on the thyroid or neck<\/a>. It can also result from autoimmune conditions, genetic mutations, or, in rare cases, magnesium imbalances. Unlike other endocrine conditions, hypoparathyroidism is distinctive because it is the only hormone deficiency disease that is <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3405491\/\" target=\"_blank\" rel=\"noreferrer noopener\">not currently treated with the missing hormone<\/a> in its standard form in Singapore, but instead managed with calcium and vitamin D supplementation.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"554\" src=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-8-1024x554.jpeg\" alt=\"Hypoparathyroidism Singapore\" class=\"wp-image-1060\" srcset=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-8-1024x554.jpeg 1024w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-8-300x162.jpeg 300w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-8-768x415.jpeg 768w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-8-1536x830.jpeg 1536w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-8.jpeg 1600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Hypoparathyroidism is a rare condition where the parathyroid glands produce too little hormone, causing low calcium and high phosphate levels in the blood.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">What causes hypoparathyroidism?&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Several different factors can lead to hypoparathyroidism, though the majority of cases are linked to surgical procedures. Understanding the underlying cause is important for diagnosis and long-term management.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Surgical causes <\/strong>\u2014 the most common cause is unintentional damage to, or removal of, the parathyroid glands during surgery on the thyroid or neck. This can occur after thyroidectomy, parathyroidectomy, or extensive surgery for head and neck cancers. Even when surgeons take care to preserve the glands, disruption of their blood supply can impair their function and this is a recognised risk.<\/li>\n\n\n\n<li><strong>Autoimmune disease <\/strong>\u2014 in some patients, the immune system mistakenly attacks the parathyroid glands, leading to their gradual destruction. This form of hypoparathyroidism may occur alone or as part of <a href=\"https:\/\/www.chop.edu\/conditions-diseases\/autoimmune-polyendocrine-syndrome\" target=\"_blank\" rel=\"noreferrer noopener\">autoimmune polyglandular syndromes<\/a>, which involve multiple hormone-producing glands. This is rare.&nbsp;<\/li>\n\n\n\n<li><strong>Genetic conditions<\/strong> \u2014 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6233988\/\" target=\"_blank\" rel=\"noreferrer noopener\">rare inherited disorders<\/a> can cause hypoparathyroidism. These include mutations affecting parathyroid gland development, isolated familial hypoparathyroidism, and conditions such as <a href=\"https:\/\/www.nhs.uk\/conditions\/digeorge-syndrome\/\" target=\"_blank\" rel=\"noreferrer noopener\">DiGeorge syndrome<\/a>, where abnormal development of the thymus and parathyroids occurs.<\/li>\n\n\n\n<li><strong>Magnesium imbalance<\/strong> \u2014 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12105390\/\" target=\"_blank\" rel=\"noreferrer noopener\">both very low and very high levels of magnesium<\/a> in the blood can interfere with parathyroid hormone secretion and action. Correcting the magnesium abnormality often restores normal parathyroid function. This can be caused by anti-acid medication causing low magnesium levels says Dr. Dinesh.&nbsp;<\/li>\n\n\n\n<li><strong>Other causes <\/strong>\u2014 less common causes include infiltration of the glands by conditions such as <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3970271\/\" target=\"_blank\" rel=\"noreferrer noopener\">haemochromatosis (iron overload)<\/a>, <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3683230\/\" target=\"_blank\" rel=\"noreferrer noopener\">Wilson\u2019s disease (copper accumulation)<\/a>, or <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6232203\/\" target=\"_blank\" rel=\"noreferrer noopener\">metastatic cancer<\/a>. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10486996\/\">Radiation therapy <\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10486996\/\" target=\"_blank\" rel=\"noreferrer noopener\">t<\/a><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10486996\/\">o the neck<\/a> can also contribute to glandular damage and hormone deficiency.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"684\" src=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-9-1024x684.jpeg\" alt=\"Parathyroid Hormone (PTH) Singapore\" class=\"wp-image-1061\" srcset=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-9-1024x684.jpeg 1024w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-9-300x200.jpeg 300w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-9-768x513.jpeg 768w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-9-1536x1025.jpeg 1536w, https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/wp-content\/uploads\/2026\/04\/image-9.jpeg 1600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Hypoparathyroidism is caused when the parathyroid glands fail to produce enough parathyroid hormone (PTH), often due to surgery, autoimmune disease, or genetic factors.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">&nbsp;What are the symptoms of hypoparathyroidism?&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The symptoms of hypoparathyroidism largely arise from low levels of calcium in the blood (hypocalcaemia) and high levels of phosphate. These imbalances affect the proper functioning of nerves and muscles, and may vary from mild to severe depending on how much calcium is lacking.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Early symptoms<\/strong> \u2014 many patients notice tingling or numbness around the mouth, fingertips, or toes. Muscle cramps, twitching, and a sense of stiffness are also common early signs. Some people may experience fatigue, irritability, or anxiety.<\/li>\n\n\n\n<li><strong>Neuromuscular symptoms <\/strong>\u2014 low calcium can make nerves and muscles more excitable, leading to painful spasms in the hands and feet (tetany). In more severe cases, involuntary contractions of the larynx (laryngospasm) can cause difficulty breathing.<\/li>\n\n\n\n<li><strong>Neurological symptoms<\/strong> \u2014 if hypocalcaemia becomes more pronounced, <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4374060\/\" target=\"_blank\" rel=\"noreferrer noopener\">seizures may occur<\/a>. Some patients may also report headaches, memory problems, confusion, or difficulty concentrating.<\/li>\n\n\n\n<li><strong>Cardiac symptoms <\/strong>\u2014 low calcium levels can affect the heart, sometimes causing abnormal rhythms (arrhythmias), low blood pressure, or palpitations.<\/li>\n\n\n\n<li><strong>Long-term features <\/strong>\u2014 chronic hypoparathyroidism may cause <a href=\"https:\/\/rarediseases.org\/rare-diseases\/hypoparathyroidism\/\" target=\"_blank\" rel=\"noreferrer noopener\">changes in the skin, hair, and nails, including dry skin, brittle nails, or coarse hair<\/a>. Dental problems such as defective enamel and delayed tooth eruption <a href=\"https:\/\/www.oooojournal.net\/article\/S1079-2104(08)00878-0\/abstract\" target=\"_blank\" rel=\"noreferrer noopener\">may appear in children<\/a>. Cataracts and <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5768156\/\" target=\"_blank\" rel=\"noreferrer noopener\">calcification in parts of the brain<\/a> (such as the basal ganglia) may develop over time if calcium control is poor.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The range and severity of symptoms often depend on how suddenly calcium levels drop. Rapid declines may trigger acute symptoms, while slower or milder reductions may go unnoticed until complications arise.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Who is at risk of hypoparathyroidism in Singapore?&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Anyone can develop hypoparathyroidism, but certain groups face a higher likelihood, particularly those undergoing thyroid or neck surgery. In Singapore, where thyroid surgery is commonly performed for both benign and malignant conditions, these risk factors are especially relevant.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Surgical causes<\/strong> \u2014 the greatest risk comes from thyroid or neck surgery, especially thyroidectomy. During these procedures, the parathyroid glands may be accidentally damaged, removed, or deprived of their blood supply, leading to hormone deficiency.<\/li>\n\n\n\n<li><strong>Extent and complexity of surgery <\/strong>\u2014 more extensive operations, such as total thyroidectomy or those involving lymph node dissections, carry a higher risk. Repeat operations or procedures for thyroid cancer increase the likelihood further.<\/li>\n\n\n\n<li><strong>Patient characteristics <\/strong>\u2014 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7225482\/\" target=\"_blank\" rel=\"noreferrer noopener\">studies<\/a> show women are more likely to develop hypoparathyroidism than men, and younger patients, <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11383864\/\" target=\"_blank\" rel=\"noreferrer noopener\">particularly under 40 years of age<\/a>, are more prone to temporary forms of the condition. Lower calcium levels before surgery may also contribute to increased risk. This may be likely to ladies having higher rates of thyroid surgery.&nbsp;<\/li>\n\n\n\n<li><strong>Vitamin D deficiency <\/strong>\u2014 despite Singapore\u2019s sunny climate, vitamin D deficiency is common due to indoor lifestyles and limited sun exposure. Low vitamin D reduces the reserve capacity of the body to raise calcium absorption, raising susceptibility to postsurgical hypoparathyroidism.<\/li>\n\n\n\n<li><strong>Autoimmune and genetic conditions<\/strong> \u2014 some people develop hypoparathyroidism due to autoimmune diseases that attack the parathyroid glands or genetic syndromes like DiGeorge syndrome, which affect their development and function.<\/li>\n\n\n\n<li><strong>Magnesium imbalance<\/strong> \u2014 low or high magnesium levels in the blood can disrupt parathyroid hormone secretion and action, triggering hypoparathyroidism. Correcting the imbalance usually restores normal function.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What are the complications of hypoparathyroidism?&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">If hypoparathyroidism is not well controlled, long-term calcium and phosphate imbalances can affect many parts of the body. The doctor will monitor these complications closely to prevent lasting damage.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Neurological complications <\/strong>\u2014 persistently low calcium may lead to seizures, cognitive difficulties, or movement problems caused by calcification in areas of the brain such as the basal ganglia.This is rare if appropriate treatment is started.&nbsp;<\/li>\n\n\n\n<li><strong>Kidney problems <\/strong>\u2014 high doses of calcium and vitamin D can raise the risk of kidney stones or kidney damage. The doctor may check urine calcium levels and kidney function regularly to reduce this risk.<\/li>\n\n\n\n<li><strong>Eye complications<\/strong> \u2014 patients can develop cataracts if calcium levels remain low over many years, leading to blurred vision or loss of clarity.<\/li>\n\n\n\n<li><strong>Dental issues <\/strong>\u2014 in children, hypoparathyroidism may cause delayed tooth eruption or enamel defects, which can affect dental development. Adults may also notice brittle teeth or other oral health problems.<\/li>\n\n\n\n<li><strong>Musculoskeletal changes <\/strong>\u2014 muscle cramps and spasms are common if calcium levels fluctuate. Over time, bones may become more fragile if calcium regulation remains unstable.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">With careful treatment and routine follow-up, many of these complications can be prevented or managed effectively. The doctor will usually individualise monitoring and treatment to minimise long-term risks and protect overall health.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How is hypoparathyroidism diagnosed?&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Doctors diagnose hypoparathyroidism by combining clinical history with blood and urine tests that reveal the typical changes in calcium, phosphate, and parathyroid hormone levels.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Blood calcium and phosphate levels <\/strong>\u2014 the doctor will usually start with a blood test. If calcium is low and phosphate is high, this strongly suggests the parathyroid glands are underactive.<\/li>\n\n\n\n<li><strong>Parathyroid hormone measurement <\/strong>\u2014 a <a href=\"https:\/\/medlineplus.gov\/lab-tests\/parathyroid-hormone-pth-test\/\" target=\"_blank\" rel=\"noreferrer noopener\">parathyroid hormone (PTH) test<\/a> is then performed. In hypoparathyroidism, PTH is either low or inappropriately normal despite low calcium, which helps distinguish it from other causes of hypocalcaemia.<\/li>\n\n\n\n<li><strong>Magnesium levels <\/strong>\u2014 the doctor may also check magnesium, since both low and high magnesium levels can interfere with parathyroid hormone function. Correcting these imbalances often improves calcium control.<\/li>\n\n\n\n<li><strong>Vitamin D status <\/strong>\u2014 a vitamin D test may be ordered to rule out deficiency, as this can complicate calcium regulation and make symptoms worse.<\/li>\n\n\n\n<li><strong>Urinary calcium excretion <\/strong>\u2014 in some cases, a 24-hour urine collection is recommended to measure calcium loss in the urine. This helps guide treatment and prevents kidney complications.<\/li>\n\n\n\n<li><strong>Clinical history and surgical background <\/strong>\u2014 the doctor will ask about recent thyroid or neck surgery, past autoimmune conditions, or any family history of endocrine disorders, as these details often explain why calcium and parathyroid hormone levels are abnormal.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What are the treatment options for hypoparathyroidism?&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">When treating hypoparathyroidism, the doctor focuses on restoring calcium and phosphate balance, easing symptoms, and preventing complications, usually through lifelong therapy tailored to each patient.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Calcium supplements <\/strong>\u2014 the doctor may recommend oral calcium tablets to bring blood calcium levels back into the normal range. The dose is adjusted according to blood test results and how well symptoms are controlled.<\/li>\n\n\n\n<li><strong>Active vitamin D analogues <\/strong>\u2014 the doctor may prescribe medications such as calcitriol to improve calcium absorption from the gut and help stabilise blood calcium levels.<\/li>\n\n\n\n<li><strong>Dietary adjustments <\/strong>\u2014 patients are often advised to eat a diet rich in calcium, including dairy products, leafy greens, and fortified foods. At the same time, limiting phosphate-rich items such as soft drinks and processed foods can help keep the balance steady.<\/li>\n\n\n\n<li><strong>Magnesium correction<\/strong> \u2014 if blood tests show low magnesium, supplementation is provided, as normal magnesium levels are vital for parathyroid hormone function.<\/li>\n\n\n\n<li><strong>Monitoring and follow-up<\/strong> \u2014 the doctor will arrange regular blood tests to check calcium, phosphate, magnesium, kidney function, and urinary calcium. This careful monitoring helps ensure treatment remains effective and reduces the risk of long-term complications such as kidney stones.<\/li>\n\n\n\n<li><strong>Parathyroid hormone replacement <\/strong>\u2014 in rare cases where standard treatment does not control symptoms or calcium balance well, the doctor may recommend recombinant <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4722396\/\" target=\"_blank\" rel=\"noreferrer noopener\">human parathyroid hormone (rhPTH)<\/a>. This option is not yet widely available and is reserved for patients with more challenging disease.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">With the right combination of medication, diet, and regular monitoring, most patients with hypoparathyroidism can achieve good control of their condition and maintain a stable quality of life.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Prognosis and living with hypoparathyroidism<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">With the right treatment and close monitoring, most patients with hypoparathyroidism can lead full and active lives. The outlook depends on how well calcium and phosphate levels are controlled and whether complications are detected early.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Long-term outlook<\/strong> \u2014 although the condition is usually lifelong, good management with calcium and vitamin D supplements allows many patients to remain symptom-free. Regular follow-up helps prevent long-term problems affecting the kidneys, brain, and eyes.<\/li>\n\n\n\n<li><strong>Quality of life <\/strong>\u2014 some patients may still notice fatigue, tingling, or cramps if calcium levels fluctuate, but these symptoms can often be managed with dose adjustments and medical supervision.<\/li>\n\n\n\n<li><strong>Daily living <\/strong>\u2014 doctors usually advise patients to stick to prescribed medications, eat a diet that supports calcium balance, and attend routine blood tests. Patients should also inform healthcare providers about their condition before surgery or when starting new medication, as this can affect calcium levels.<\/li>\n\n\n\n<li><strong>Prognosis with advanced therapies <\/strong>\u2014 in selected cases, where conventional treatment does not provide stable control, parathyroid hormone replacement can improve quality of life, although it is not yet widely available.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">With consistent medical care, most people with hypoparathyroidism can expect to live normal lifespans and maintain a stable quality of life. The key is regular monitoring, early recognition of complications, and a treatment plan tailored to each patient\u2019s needs.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hypoparathyroidism, or underactive parathyroid, is a rare condition where the parathyroid glands do not produce enough parathyroid hormone, leading to low calcium and high phosphate levels in the blood. It most often occurs after thyroid or neck surgery, but can also result from autoimmune disease, genetic syndromes, or magnesium imbalances. With careful medical care, most patients can achieve good control and maintain a stable quality of life.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you are experiencing symptoms of low calcium or were diagnosed with hypoparathyroidism after thyroid or neck surgery, <a href=\"https:\/\/glutenfreepleasure.com\/__proxy_domain\/themetabolicclinic.com.sg\/contact\/\" type=\"page\" id=\"194\">schedule a consultation<\/a> with The Metabolic Clinic for expert evaluation and tailored management.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions (FAQs)&nbsp;<\/h2>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"alignnone\"><style>#sp-ea-1050 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-1050.sp-easy-accordion>.sp-ea-single {margin-bottom: 10px; border: 1px solid #e2e2e2; }#sp-ea-1050.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #feffed;}#sp-ea-1050.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #fff; color: #183122;}#sp-ea-1050.sp-easy-accordion>.sp-ea-single {background: #667861;}#sp-ea-1050.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: left; color: #444;font-size: 16px;}<\/style><div id=\"sp_easy_accordion-1750231607\"><div id=\"sp-ea-1050\" class=\"sp-ea-one sp-easy-accordion\" data-ea-active=\"ea-click\" data-ea-mode=\"vertical\" data-preloader=\"\" data-scroll-active-item=\"\" data-offset-to-scroll=\"0\"><div class=\"ea-card ea-expand sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10500\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10500\" aria-controls=\"collapse10500\" href=\"#\" aria-expanded=\"true\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-minus\"><\/i> What triggers acute episodes in hypoparathyroidism?<\/a><\/h3><div class=\"sp-collapse spcollapse collapsed show\" id=\"collapse10500\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10500\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Acute episodes, such as muscle spasms or tingling, are often triggered by sudden drops in calcium caused by illness, stress, medication changes, or poor absorption.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10501\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10501\" aria-controls=\"collapse10501\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Does hypoparathyroidism increase the risk of heart rhythm problems?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10501\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10501\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, persistent low calcium levels in hypoparathyroidism can disrupt the heart\u2019s electrical activity and increase the risk of irregular rhythms.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10502\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10502\" aria-controls=\"collapse10502\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> How does hypoparathyroidism affect children differently from adults?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10502\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10502\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Children with hypoparathyroidism may experience delayed growth, enamel defects, or developmental problems, whereas adults often present with neurological or muscular symptoms.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10503\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10503\" aria-controls=\"collapse10503\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> What autoimmune disease causes hypoparathyroidism?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10503\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10503\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Autoimmune hypoparathyroidism occurs when the immune system attacks the parathyroid glands. It may appear on its own or as part of autoimmune polyglandular syndrome type 1 (APS-1), a rare disorder that also affects other hormone-producing glands.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10504\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10504\" aria-controls=\"collapse10504\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Are there non-surgical causes of hypoparathyroidism besides autoimmune and genetic factors?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10504\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10504\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, conditions such as low magnesium, iron or copper overload, radiation to the neck, and rare receptor abnormalities can also result in hypoparathyroidism.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10505\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10505\" aria-controls=\"collapse10505\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Is there a risk of hypercalcaemia from treatment of hypoparathyroidism?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10505\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10505\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, taking too much calcium and vitamin D can raise calcium to unsafe levels, leading to kidney stones or damage if not monitored.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10506\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10506\" aria-controls=\"collapse10506\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can hypoparathyroidism cause changes to skin, hair, or nails?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10506\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10506\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Long-term hypoparathyroidism may lead to dry skin, brittle nails, and coarse hair due to persistent calcium imbalance.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10507\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10507\" aria-controls=\"collapse10507\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Does hypoparathyroidism affect mental clarity or mood?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10507\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10507\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, people with hypoparathyroidism sometimes experience brain fog, mood changes, or difficulty concentrating when calcium levels are unstable.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10508\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10508\" aria-controls=\"collapse10508\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can hypoparathyroidism lead to cataract formation?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10508\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10508\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Chronic low calcium in hypoparathyroidism can cause cataracts to develop earlier than expected, resulting in blurred or cloudy vision.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-10509\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse10509\" aria-controls=\"collapse10509\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Are emergency measures needed for sudden worsening of hypoparathyroidism?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse10509\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-10509\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, severe hypocalcaemia may require urgent hospital treatment with intravenous calcium to prevent seizures or life-threatening complications.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105010\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105010\" aria-controls=\"collapse105010\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can pregnancy worsen hypoparathyroidism?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105010\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105010\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Pregnancy may make calcium control more difficult in women with hypoparathyroidism, so closer monitoring and treatment adjustments are often required.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105011\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105011\" aria-controls=\"collapse105011\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Is hypoparathyroidism linked with seizures?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105011\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105011\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, seizures can occur in hypoparathyroidism if calcium levels drop too low and are not corrected promptly.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105012\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105012\" aria-controls=\"collapse105012\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Is hypoparathyroidism related to thyroid disease?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105012\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105012\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Yes, the most common cause of hypoparathyroidism is accidental damage to the parathyroid glands during thyroid surgery.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105013\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105013\" aria-controls=\"collapse105013\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> Can hypoparathyroidism cause weight gain?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105013\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105013\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Hypoparathyroidism itself does not directly cause weight gain, but low calcium, fatigue, and muscle cramps can reduce physical activity. In some patients, long-term medication and changes in metabolism may also contribute to gradual weight gain.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105014\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105014\" aria-controls=\"collapse105014\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> How long can you live with hypoparathyroidism?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105014\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105014\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">With proper treatment and regular monitoring, people with hypoparathyroidism can usually live a normal lifespan. Lifelong follow-up is important to keep calcium stable and prevent complications affecting the kidneys, heart, or brain.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105015\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105015\" aria-controls=\"collapse105015\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> What age does hypoparathyroidism start?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105015\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105015\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">Hypoparathyroidism can begin at any age. It often appears suddenly after thyroid or neck surgery in adults, but genetic or autoimmune forms may present in childhood or adolescence.<\/span><\/p><\/div><\/div><\/div><div class=\"ea-card sp-ea-single\"><h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-105016\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse105016\" aria-controls=\"collapse105016\" href=\"#\" aria-expanded=\"false\" tabindex=\"0\"><i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i> What happens if hypoparathyroidism goes untreated?<\/a><\/h3><div class=\"sp-collapse spcollapse \" id=\"collapse105016\" data-parent=\"#sp-ea-1050\" role=\"region\" aria-labelledby=\"ea-header-105016\"> <div class=\"ea-body\"><p><span style=\"font-weight: 400\">If hypoparathyroidism is left untreated, low calcium can cause persistent muscle cramps, tingling, and fatigue, and may progress to seizures, heart rhythm problems, cataracts, or kidney damage. Over time, it can seriously affect quality of life and overall health.<\/span><\/p><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>A condition characterised by low parathyroid hormone levels, leading to low blood calcium and muscle or nerve symptoms.<\/p>\n","protected":false},"author":1,"featured_media":1061,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"page_category":[15],"class_list":["post-65","page","type-page","status-publish","has-post-thumbnail","hentry","page_category-bone-health-osteoporosis"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hypoparathyroidism Singapore | Underactive Parathyroid<\/title>\n<meta name=\"description\" content=\"Learn about hypoparathyroidism and underactive parathyroid glands in Singapore, including causes, symptoms, 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